What is breast cancer?4 min read

Other genes linked to breast cancer

BRCA gets the attention, but several other genes can also raise breast cancer risk. Most are rare — and they are usually only tested when family history suggests them.

Alongside BRCA1 and BRCA2, genes such as PALB2, CHEK2, ATM, TP53 and PTEN have been linked to an increased risk of breast cancer. Together they account for a small share of hereditary risk.

Why they matter

  • They can raise risk moderately or strongly, depending on the gene
  • They often overlap with other cancer risks in the family
  • Testing is usually done via a panel, guided by family history

The practical message is the same: hereditary risk, whatever the gene, should be managed with a doctor through tailored screening and prevention, not through fear.

In brief

Most breast cancers are not hereditary
Non-BRCA genes explain a small share of cases
Panel testing is guided by family history

What you can do

Share your family story

Detailed history helps choose the right test.

Let results shape your plan

Any hereditary risk deserves a personalised screening plan.

Keep learning

Genetic testing for breast cancerAwarenessBRCA: the breast cancer geneAwarenessBreast cancer risk factorsAwareness