Unlike chemotherapy, which hits all fast-growing cells, targeted therapy focuses on features unique to cancer cells. The best-known targets are HER2 and, more recently, markers used by immunotherapy.
Examples of targeted approaches
- Anti-HER2 drugs for HER2-positive cancers
- CDK4/6 inhibitors for advanced hormone-positive disease
- PARP inhibitors for BRCA-related cancers
- Immunotherapy to help the immune system attack the cancer
Because these drugs are selective, their side effects are often different and lighter than chemotherapy. Targeted therapy is one reason advanced breast cancer has become a long-term condition.